I would keep reading. Minor quibbles.

It is not known who created 'The Path'. Many believe that an ancient, highly advanced civilization constructed the galactic interstellar highways with [unimaginable] ADVANCED [I'm not sure what's unimagineable!] technological power, expanding their empire across the galaxy before moving on. [Why moving on?]

Some believe it was the gods themselves who used their infinite power to connect the farthest reaches of the galaxy. Several civilizations have taken to religion to explain the path because no technologies have proved sufficient enough to open the portals.[In that case, how do we know they're portals? Also, has any atheist really taken to religion because of an unexplained physical phenomenon?]

One of the religious sects believe the ancient founders of the path were the gods’ chosen people and therefore were given by divine right the means to open the gateways to the galaxy...

(1) “It is not known who…” is passive. The sentence would be stronger if you changed it to something active, like “No one knows who,” or just take out that first sentence all together. The rest of the paragraph implies that no one knows, because there are so many theories about it.
(2) You have several phrases that could be replaced with one strong verb, or a trimming of the sentence. For example, the second sentence could be “Many believe that an ancient civilization created the interstellar highways, expanding their empire across the galaxy before moving on.”
(3) This paragraph is muddled. “Others civilizations believe the gods themselves built…”

You have an interesting opening here. Several things that caught my attention were
(1) The potential conflict between those with the divine right, and the others who will envy that right.
(2) The conflict between religion and secular explanations. I suppose both have proof for what they believe?
Like wbriggs said, I wonder if you need this prologue. Is this all information that the read needs to know? And if so, could it be dispersed gradually throughout the story?

If the book is mostly about this civilization, then you should consider whether or not you want to write about something so uninvolved emotionally. There is always the danger of it reading like a history text.

I would read beyond this, but if I found that the book was about the history of an ancient race, and not about specific people, then I would put it down. But that might be my preference. After all, I put down Asimov’s Foundation trilogy.

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It is not known who created 'The Path'. Many believe that an ancient, highly advanced civilization constructed the galactic interstellar highways[. If you don't end here, I begin to drift. IMHO: skip with and continue with They used] unimaginable technological power [cut-->,] expanding their empire across the galaxy[,] before moving on.
Some believe [needed?-->it was] the gods [needed?--> themselves who] used their infinite power to connect the farthest reaches of the galaxy. [from this point on, it seems that you are redefining your first sentence. If you are going to investigate The Path from a religious PoV, IMHO, you should do so from the beginning -- and from a believer's perspective.] Several civilizations have taken to religion to explain the path because no technologies have proved sufficient enough to open the portals.
One of the religious sects believe the ancient founders of the path were the gods’ chosen people and therefore were given by divine right the means to open the gateways to the galaxy...

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